Form 8-K · Current Report · Filed 2024-03-12
Crinetics Pharmaceuticals Announces Positive Topline Results from Phase 2 Study of Paltusotine for Carcinoid Syndrome
Crinetics Pharmaceuticals, Inc. announced positive topline results from its open-label Phase 2 study of paltusotine, an oral, once-daily investigational compound for the treatment of carcinoid syndrome. The study demonstrated rapid and sustained reductions in the frequency and severity of flushing episodes and bowel movements, with paltusotine being generally well-tolerated. The Company plans to engage with the FDA to align on a Phase 3 study design and has begun preparations to initiate a Phase 3 program by the end of the year.
- Filer
- Crinetics Pharmaceuticals Inc. CRNX · NASDAQ
- Filed
- Accession
- 0001193125-24-065913
- CIK
- 0001658247
- Signal
- Low impactHealthcare
- Source
- Official filing on sec.gov ↗
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Exhibits (2)
About Crinetics Pharmaceuticals Inc.
Crinetics Pharmaceuticals Inc. is a biopharmaceutical company dedicated to the development of novel therapeutics for patients with endocrine conditions and other rare diseases. The primary focus of Crinetics is on crafting oral therapies that target hormone receptors, offering significant potential to transform the treatment landscape for several disorders. The company's pipeline includes investigational drugs such as paltusotine and CRN04894, aimed at addressing conditions like acromegaly and congenital adrenal hyperplasia, respectively. Crinetics combines cutting-edge drug discovery with an in-depth understanding of disease biology to impact the field of endocrinology substantially. By specializing in small molecules, Crinetics Pharmaceuticals seeks to provide new treatment options that enhance patient quality of life and address significant unmet medical needs. Headquartered in San Diego, California, the enterprise collaborates with academic institutions and industry partners to position its innovations at the forefront of medical advancement. Its work holds significant potential to influence the pharmaceutical industry, contributing to the expansion of targeted therapies within niche markets where few options currently exist.
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