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Form 8-K · Current Report · Filed 2025-11-06

Crinetics Pharmaceuticals Reports Third Quarter 2025 Financial Results and Business Update

Crinetics Pharmaceuticals, Inc. reported its financial results for the third quarter ended September 30, 2025, with a net loss of $130.1 million, compared to a net loss of $76.8 million for the same period in 2024. The company launched PALSONIFY, its first FDA-approved treatment for acromegaly, which has seen positive uptake and reimbursement trends. Crinetics is advancing multiple clinical trials across its pipeline, with key milestones expected in the fourth quarter of 2025 and early 2026. The company expects cash, cash equivalents, and investments to fund its operations into 2029.

Filer
Crinetics Pharmaceuticals Inc. CRNX · NASDAQ
Filed
Accession
0001658247-25-000018
CIK
0001658247
Signal
Low impactHealthcare

Items reported

Item 2.02

Results of Operations and Financial Condition

General Statement
Item 9.01

Financial Statements and Exhibits

Exhibits Furnished

Market reaction

Close before filing

$42.53

Next session

-5.9%

Since filing

+96.4%

Latest close

$83.52

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Precedent

Previous filings from CRNX reporting the same item, with the next session's move:

About Crinetics Pharmaceuticals Inc.

Crinetics Pharmaceuticals Inc. is a biopharmaceutical company dedicated to the development of novel therapeutics for patients with endocrine conditions and other rare diseases. The primary focus of Crinetics is on crafting oral therapies that target hormone receptors, offering significant potential to transform the treatment landscape for several disorders. The company's pipeline includes investigational drugs such as paltusotine and CRN04894, aimed at addressing conditions like acromegaly and congenital adrenal hyperplasia, respectively. Crinetics combines cutting-edge drug discovery with an in-depth understanding of disease biology to impact the field of endocrinology substantially. By specializing in small molecules, Crinetics Pharmaceuticals seeks to provide new treatment options that enhance patient quality of life and address significant unmet medical needs. Headquartered in San Diego, California, the enterprise collaborates with academic institutions and industry partners to position its innovations at the forefront of medical advancement. Its work holds significant potential to influence the pharmaceutical industry, contributing to the expansion of targeted therapies within niche markets where few options currently exist.

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