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Form 8-K · Current Report · Filed 2025-09-29

Metsera Announces Positive Phase 2b Results for MET-097i

On September 29, 2025, Metsera, Inc. announced positive topline data from two Phase 2b trials of MET-097i, a GLP-1 receptor agonist. In VESPER-1, the drug demonstrated mean placebo-subtracted weight loss of up to 14.1% after 28 weekly doses, with potentially class-leading tolerability. The company plans to initiate a global Phase 3 program in late 2025 based on these results.

Filer
MTSR MTSR
Filed
Accession
0001193125-25-223440
CIK
0002040807
Signal
Medium impact

Items reported

Item 7.01

Regulation FD Disclosure

Regulation FD Disclosure
Item 8.01

Other Events

Product Launch

Market reaction

Close before filing

$52.25

Next session

+0.2%

Since filing

+34.9%

Latest close

$70.50

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