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Form 8-K · Current Report · Filed 2026-08-05

Revolution Medicines Files NDA for Daraxonrasib and Receives Breakthrough Therapy Designation

Revolution Medicines, Inc. announced its financial results for the quarter ended June 30, 2026, and provided an update on corporate progress. The company reported that the U.S. FDA accepted its New Drug Application (NDA) for daraxonrasib for the treatment of previously treated metastatic pancreatic cancer. Additionally, the FDA granted Breakthrough Therapy Designation to daraxonrasib for certain patients with previously treated metastatic RAS mutant non-small cell lung cancer. The company also achieved U.S. commercial launch readiness and began submissions to the European Medicines Agency under a new phased review process. Revolution Medicines continues to advance its broad RAS-targeted portfolio in non-small cell lung cancer and pancreatic cancer.

Filer
Revolution Medicines Inc. RVMD · NASDAQ
Filed
Accession
0001193125-26-335039
CIK
0001628171
Signal
Medium impactHealthcare

Items reported

Item events

Reported Item

New Major Contract

Market reaction

Close before filing

$193.46

Since filing

+0.0%

Latest close

$193.46

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Insider tape

Within 45 days of this filing, RVMD insiders reported 17 Form 4 transactions — net selling of $3.9M.

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About Revolution Medicines Inc.

Revolution Medicines Inc. is a biotechnology company primarily focused on the development of targeted therapies for cancer treatment. The company aims to create innovative drugs by leveraging the potential of inhibitors that target specific oncogenic pathways. Revolution Medicines Inc. specializes in synthetic lethal technologies and non-covalent inhibitors to address complex molecular targets found in cancer cells. With a strong emphasis on research and development, it collaborates with academic institutions and partners within the biopharmaceutical industry to advance its pipeline of drug candidates. Revolution Medicines Inc. is significantly involved in the oncology sector, with potential impacts on patient care through its commitment to developing precision medicines. As a key player in the biotech landscape, the company contributes to the ongoing evolution of cancer treatment methodologies, seeking to extend and improve patients' lives through state-of-the-art therapeutic options.

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